Before using, check this product visually for particles or discoloration. Do not share your drugs with others and do not take anyone else's drugs. Venofer pregnancy and breastfeeding warnings. But some people have a delayed allergic reaction to certain drugs. Here are answers to some frequently asked questions about Injectafer. Instead, youll start by receiving just one treatment course of Injectafer. Its not known whether its safe to breastfeed while youre taking Injectafer. FG Trade/E+ sia Getty Images (A medication class describes a group of drugs that work in the same way.). Side effects from HRT depend on a number of factors: Dizziness. 2005 - 2023 WebMD LLC. On day three I had a headache and felt heavy/exhausted, which lasted a few days. These are not all of the side effects that may occur. Theyll likely have you stop taking the pills while youre using Injectafer. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. You may report side effects to FDA at 1-800-FDA-1088. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Injectafer is a brand-name prescription drug. You will need to talk about the benefits and risks to you and the baby. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. You may also report side effects at https://www.fda.gov/medwatch. You should always consult your doctor or another healthcare professional before taking any medication. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Iron infusions are given directly into a vein. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Sharing this information can help you avoid potential interactions. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. experience severe side effects, please seek medical attention right away and notify the ordering physician. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. With slow IV injection, the drug is given as a single, slow injection into your vein. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Venofer is given as an infusion into a vein. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. 4 0 obj monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. Ask your doctor or healthcare provider if Venofer is the right choice for you. Consult your doctor before breast-feeding. Injectafer and Venofer are both brand-name drugs. But for other people, their anemia may come back after Injectafer treatment. Injectafer and Venofer can cause very similar side effects, but some different ones as well. ByDr. Orofer S 50 Injection 1 Injection in 1 Packet 147. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. If needed, theyll recommend treatment, including certain medications. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Examples of thisinclude: Not allside effectslast forever. Innovators Monograph Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Venofer treatment may be repeated if iron deficiency reoccurs. After the infusion, you can drive yourself home and return to your usual activities. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Here's some detail on certain side effects this drug may cause. Have blood work checked as you have been told by the doctor. No, you wont need to take iron pills while youre using Injectafer. There are 2 tests that your doctor will likely I was surprised too but the Dr said it definitely sounds like a reaction. But for other people, their IDA returns after treatment with Injectafer. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ You may report side effects to FDA at 1-800-FDA-1088. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. I had Venofer infusions, 2 rounds now in the span of three years. Change in taste. Some may be a better fit for you than others. Does Venofer Vial interact with other drugs you are taking? These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Be ready to tell or show what was taken, how much, and when it happened. Properly discard this product when it is expired or no longer needed. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Yes, in some cases it may. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. These nutrients include iron, vitamin B12, and folate. Do not exceed 1,500 mg of iron per dosing course. And this can lead to anemia, including IDA. (And Injectafer is used to treat IDA.) Allergic reactions typically occur the first time your body is exposed to a drug. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Your doctor will do laboratory tests to monitor your response. This means you would get two Injectafer doses of 720 mg each. Theyll do this by checking certain blood tests. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Should I avoid certain foods while taking Venofer Vial? The iron released by this drug does pass into human breast milk. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. A shortage of iron can cause health problems. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Blood tests may be needed to check for unwanted effects. Always review your medical history with the treatingphysician. intense abdominal pain. Version: 7.01. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. An iron infusion is a way to increase the body's iron levels quickly. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. There are currently no generic forms of either drug. Injectafer infusions are given over a period of at least 15 minutes. cough. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. The infusion will take between 15-30 minutes if it is given in. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Depending on your doctors instructions and What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Once inside your body, ferric carboxymaltose releases iron into your system. During pregnancy, this medication should be used only when clearly needed. Which tests can diagnose iron deficiency anemia? For additional information, contact your healthcare provider. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. %PDF-1.3 Its not known if Injectafer is safe to use during pregnancy. Consult your pharmacist or local waste disposal company. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. The drug helps increase your hemoglobin level back to a value thats within the normal range. However, side effects at the 150 mg dose may indicate that you might not . Both Injectafer and Venofer belong to a class of medications called iron replacement products. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. This is not a complete list of possible side effects. The benefit of treating your condition during pregnancy may outweigh any risks. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. There have also been reports of serious allergic reactions to Venofer. Things to remember when you fill your prescription. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Can diet help improve depression symptoms? These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). These people may lose weight as their anemia improves because theyre more active. other treatments you receive, you will need to go back for several treatments with Venofer. This website is intended for use by US patients. US residents can call their local poison control center at 1-800-222-1222. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. muscle pain. This site is intended for use only by US patients. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. No, you most likely wont take Injectafer long term. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Keep all drugs in a safe place. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Venofer injection contains iron sucrose, a form of the mineral iron. The following lists contain some of the key side effects that may occur while taking Injectafer. chest pain. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. If either is present, do not use the liquid. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Follow your doctor's directions carefully. Venofer is for use in adults and children at least 2 years old. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). What is Venofer? You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Check with your pharmacist if you have questions about the best way to throw out drugs. Injectafer contains the active drug ferric carboxymaltose. These are not all the side effects that may occur; contact your healthcare provider if you have questions. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. (Hemoglobin is a protein thats found in your red blood cells.). Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Why is the range so wide? Terminal half-life ranges from 7 to 12 hours. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Medically reviewed by Sanjai Sinha, MD. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. You may report side effects to the FDA at 1-800-332-1088. All rights reserved. Youll receive doses of Injectafer from a healthcare professional at a medical facility. If you have diarrhea while youre taking Injectafer, call your doctor. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Your healthcare provider will watch you closely for 30 minutes after each dose. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Some people only need one treatment course of Injectafer. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. If you have questions about side effects, call your doctor. Its not known if Injectafer is safe to take during pregnancy. Together, they can recommend ways to help you manage a body weight thats healthy for you. One of the most commonly used tests to monitor IDA is the hemoglobin test. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. How is Venofer (iron sucrose) given? If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. stream Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Venofer Side Effects. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. And these two doses need to be separated by at least 7 days. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. In Canada - Call your doctor for medical advice about side effects. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Tell all of your health care providers that you take Venofer. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Understanding what thoseside effectsare can lead to a strategy to prevent them. You may need extra iron because of blood loss during kidney dialysis. Following an LSD trip, users may experience a sort of 'comedown.'. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Available for Android and iOS devices. * Sex and gender exist on spectrums. Iron infusion benefits. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Can poor sleep impact your weight loss goals? <> These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Evenbirth controlcan lead to severeside effectslike bloodclots. reactions at the site of the injection. HRT, like other medications, does have some side effects and these are thought to be quite common. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Injectafer isnt available in a generic form. *Patients are calculated based on an estimated annual cumulative dose. fever. A variety of tests can diagnose iron deficiency anemia. 1 0 obj Renal elimination is negligible. If you notice other effects not listed above, contact your doctor or pharmacist. Headache. The insurance company will review the prior authorization request and decide if the drug will be covered. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. (Hemoglobin is a protein thats found inside your red blood cells.). Low blood pressure. This document does not contain all possible drug interactions. Details. Side effects are uncomfortable reactions to medications or drugs. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Dizziness. For example: Say you weigh 105 pounds (about 48 kilograms). (A class of medications describes a group of drugs that work in the same way.). endobj For people with certain medical implants, such as pacemakers, an MRI may pose an . They can recommend if this is safe for you to do. These side effects may include constipation and diarrhea. Throw away unused or expired drugs. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Upset stomach or throwing up. Feraheme also comes as a liquid thats given by IV infusion. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Any long-term side effects/dangers from iron infusions? If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes This survey is being conducted by the WebMD marketing sciences department. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. This information is not specific medical advice and does not replace information you receive from the healthcare provider. If these effects continue or worsen, tell your doctor.